Blood & Iron · Heart & Circulation · Methylation · Women's Health

5-MTHF 5 mg – 90 servings

Name: 5-MTHF 5 mg
Rating: 4.8 (16 reviews)

✓90-DAY MONEY-BACK GUARANTEE

$59.99$0.66 PER SERVING

Five times the dose, for people who have been told they need it. The finished form of folate, ready the moment it arrives, at a full 8,500 mcg DFE of Quatrefolic® in a single capsule. Most people do not need this much, and we would rather say so. It exists for those who genuinely do.*

Folate in its finished form

Supports normal energy metabolism

Supports red blood cell formation

Supports healthy cell division

Supports normal homocysteine metabolism

A premium branded folate

THIRD-PARTY TESTEDcGMP FACILITYVEGAN CAPSULENON-GMOCOA PER LOTGLUTEN-FREE

How to take

Take 1 capsule daily with food, or as directed by a qualified healthcare professional.. Consistency matters more than timing — pick a moment you'll remember daily.

Consult a healthcare professional before use if pregnant or nursing, taking medication, or if you have a medical condition. Keep out of reach of children.

Quality & testing

Manufactured in the USA in a cGMP-certified facility. Raw materials are tested and qualified before use, and every finished batch is verified by an independent lab for identity, potency, heavy metals, and microbials. Results publish on this page per lot.

Shipping & subscription

Subscribe at any frequency — every month, every 2 months or every 3 months — and save 10%. Subscribe to a second product and every subscription goes to 20%. Free shipping on subscriptions, and you can pause, skip or cancel anytime from your account — no phone calls, no hoops.

What it supports

Folate in its finished form

Folic acid is a starting material the body has to convert first. This is the form that arrives ready to use.

Supports normal energy metabolism

Folate is a cofactor in the everyday cellular work that turns food into usable energy.

Supports red blood cell formation

Your body makes new red blood cells constantly, and folate is one of the nutrients that job depends on.

Supports healthy cell division

Folate is required for DNA synthesis, which is why it matters most in tissues that renew quickly.

Supports normal homocysteine metabolism

Folate is part of the pathway the body uses to keep homocysteine within its normal range.

A premium branded folate

Quatrefolic®, with the exact amount printed on the label and no proprietary blend.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Folate, in its finished form.

Quatrefolic® L-5-MTHF — 8,500 mcg DFE folate per capsule

	Quatrefolic® 8,500 mcg DFE	Folic acid supplements	Folate in a multivitamin
Premium branded folate	●	—	Varies
The finished form, not a precursor	●	—	Varies
A full dose in one capsule	●	Varies	—
Exact amount disclosed	●	●	Varies
No proprietary blend	●	Varies	—
COA published every lot	●	—	—

GENERAL FORM COMPARISON — INDIVIDUAL PRODUCTS VARY BY BRAND

What's happening
while you wait.

*INDIVIDUAL RESULTS VARY. THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FDA.

Inside the formula

Quatrefolic® L-5-MTHF — 8,500 mcg DFE folate per capsule

This is the same folate as our 1 mg at five times the strength. Folic acid is a starting material the body has to convert first; the finished form does not ask that. Quatrefolic® is a premium branded folate and we use it because with this nutrient the quality of the ingredient counts as much as the number on the front. Be clear about what this is, though: 8,500 mcg DFE is deliberately high. Most people do not need it. It exists for those who have been told they do.

CUSTOMER REVIEWS

4.8 /5 ★

Based on 16 reviews

100%

Would recommend this supplement

Customers say

✦ Summarised from customer reviews.

Reviewers frequently say they were looking specifically for a 5 mg methylfolate without a large vitamin blend, and several mention being surprised the capsule is small given the strength. Ease of swallowing, no taste and no stomach upset are the most repeated observations. Some reviewers note they do not take it every day, and one is still deciding whether 5 mg is more than they personally need — a point the product page makes too, since this is a high-potency formula rather than a default choice.

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Frequently asked
questions

How do I know what's on the label is in the bottle?

Trust should be verifiable. Every batch we produce is tested by an independent laboratory, and the certificate of analysis for your exact lot is published on this page — potency, heavy metals, microbials. Testing begins the moment a raw material arrives, continues through production, and no batch is released until every result clears. The label is a claim. The COA is the proof.

How do you choose your ingredients and doses?

We formulate from peer-reviewed clinical research and dose to match it. We select the highest-grade material available for each ingredient, in the form the body absorbs best, and where a patented or branded form is the one that has actually been studied, that is the one we use. Every active appears at its exact amount, with no proprietary blends and nothing added that doesn't need to be there.

Where are CoreLabs supplements made?

In our own cGMP-certified facility in California's Central Valley. Manufacturing in-house means quality is our responsibility at every step rather than a supplier's promise. Raw materials are purchased through established US suppliers who import and qualify them, and every material is tested against our own specification before it enters production — wherever it originated.

Why are CoreLabs supplements more expensive?

Because of what goes in. We buy the highest grade of each raw material, in the most absorbable form, and we work with the branded and patented ingredient houses whose material the clinical research was actually run on — names like Lonza, Albion, RIBUS, Sabinsa and Indena. Wherever possible those materials are made domestically. Our capsules are titanium-dioxide free. Then it is made in our own facility and third-party tested batch by batch. Every one of those choices costs more than the alternative, and the price reflects it. Anyone can claim quality — we publish ours.

How is this different from folic acid?

Folic acid is a starting material — the body converts it through several steps before a cell can use it. L-5-MTHF is the finished form, so it arrives ready to use without that conversion.

What is Quatrefolic®?

A premium branded folate from Gnosis, and we use it because with this nutrient the quality of the ingredient counts as much as the amount. Every lot is tested and the certificate published.

Can I take it with other supplements?

Yes, with one check first. Many multivitamins and prenatals already contain folate, and there is no reason to stack several sources.

Should I speak to a professional first?

If you are pregnant, planning to be, or taking any medication, yes. Folate is one of the nutrients most worth getting personal advice on rather than guessing.

How is this different from your 1 mg?

Same Quatrefolic® folate, five times the amount — 8,500 mcg DFE instead of 1,700. Most people are better served by the 1 mg. This one exists for those who have been told they need the higher amount.

How long does a bottle last?

Ninety capsules at one a day is three months.